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University of Washington Immunology
The Department of Immunology is a basic science department within the University of Washington, School of Medicine located in Seattle.
Our mission in the Department of Immunology is to advance understanding of the function of the immune system in order to enhance our ability to fight infectious disease, cancer and autoimmune disease. Basic research of all aspects of immunology is critical to this mission, as well as translational research to link our findings to the development of new therapies.
We hold diversity and inclusiveness as core values in our department and emphasize their importance throughout our research, education and practice. We strive to create a climate that fosters belonging, respect and value for all within our scientific community and the institution.
GM-CSF is not essential for experimental autoimmune encephalomyelitis but promotes brain-targeted disease. Pierson ER, Goverman JM. JCI Insight. 2017 Apr 6;2(7):e92362. doi: 10.1172/jci.insight.92362. PubMed PMID: 28405624; PubMed Central PMCID: PMC5374070.
Local Inflammatory Cues Regulate Differentiation and Persistence of CD8+ Tissue-Resident Memory T Cells. Bergsbaken T, Bevan MJ, Fink PJ.Cell Reports 2017 Apr 4;19(1):114-124. doi: 10.1016/j.celrep.2017.03.031. PubMed PMID: 28380351.
RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation Brian P. Daniels, Annelise G. Snyder, Tayla M. Olsen, Susana Orozco, Thomas H. Oguin III, Stephen W.G. Tait, Jennifer Martinez, Michael Gale Jr., Yueh-Ming Loo, Andrew Oberst
Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein Gladys J. Keitany, Karen S. Kim, Akshay T. Krishnamurty, Brian D. Hondowicz, William O. Hahn, Nicholas Dambrauskas, D. Noah Sather, Ashley M. Vaughan, Stefan H.I. Kappe, Marion Pepper. . 2016. Cell Reports , Volume 17 , Issue 12 , 3193 - 3205.
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. von Moltke J, Barrett NA, Kanaoka Y, Austen KF, Locksley RM (2017). Journal of Experimental Medicine 214(1): 27-37.
Cutting Edge: Enhanced clonal burst size corrects an otherwise defective memory response by CD8+ recent thymic emigrants. Deets. K.A.1, A.M. Berkley1, T. Bergsbaken, and P.J. Fink. 2016. (1: authors contributed equally) J. Immunol. 196:2450-2455. PMCID: PMC4779721
A new Cell paper published by the Oberst Lab reveals breakthrough findings indicating an unexpected diversity in the outcomes of RIPK1...
Congratulations to Dr. Jeff Duggan for successfully defending his dissertation on Friday, March 10, 2017. His dissertation title is “BCAP functions as a dynamic regulator of hematopoiesis and...
Generating protective immunity against the early liver stage of malaria infection is feasible but has been difficult to achieve in regions with high rates of malaria infection. Researchers at the...
Congrats to UW Immunology Assistant Professor, Dr. Jakob von Moltke who received the Damon Runyon-Dale F. Frey Award for Breakthrough Scientists. This award provides additional funding to...
EVERY COUPLE OF WEEKS, an eagerly awaited package arrives at a University of Washington research lab in South Lake Union. Inside, nestled in dry ice, are special chemical compounds that...
Congratulations to Dr. Kathleen Pestal for successfully defending her dissertation on Monday, November 21, 2016. Her dissertation title is “The Role of ADAR1 in Innate Immune Regulation and Cell...