August 12, 2021
Publication Alert – Immunology study shows antiviral variant outwits several dangerous viruses.
Congratulations to the Ram Lab on the international, multi-institutional study led by Frank W. Soveg, PhD, a recent graduate student in the Ram Lab and Johannes Schwerk, PhD, acting instructor, and senior author Dr. Ram Savan, Associate Professor in immunology at the UW School of Medicine. All are also members of the UW Center for Innate Immunity and Immune Disease.
Check out the UW Medicine newsroom story.
Endomembrane targeting of human OAS1 p46 augments antiviral activity.
Soveg FW, Schwerk J, Gokhale NS, Cerosaletti K, Smith JR, Pairo-Castineira E, Kell AM, Forero A, Zaver SA, Esser-Nobis K, Roby JA, Hsiang TY, Ozarkar S, Clingan JM, McAnarney ET, Stone AE, Malhotra U, Speake C, Perez J, Balu C, Allenspach EJ, Hyde JL, Menachery VD, Sarkar SN, Woodward JJ, Stetson DB, Baillie JK, Buckner JH, Gale M Jr, Savan R. Elife. 2021 Aug 3;10:e71047. doi: 10.7554/eLife.71047.